Phase‐based arterial input function measurements for dynamic susceptibility contrast MRI

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Evaluation of signal formation in local arterial input function measurements of dynamic susceptibility contrast MRI.

Correct arterial input function (AIF) measurements in dynamic susceptibility contrast-MRI are crucial for quantification of the hemodynamic parameters. Often a single global AIF is selected near a large brain-feeding artery. Alternatively, local AIF measurements aim for voxel-specific AIFs from smaller arteries. Because local AIFs are measured higher in the arterial-tree, it is assumed that the...

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Compared to gold-standard measurements of cerebral perfusion with positron emission tomography using H(2)[(15)O] tracers, measurements with dynamic susceptibility contrast MR are more accessible, less expensive, and less invasive. However, existing methods for analyzing and interpreting data from dynamic susceptibility contrast MR have characteristic disadvantages that include sensitivity to in...

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Automated Determination of Arterial Input Function for Dynamic Susceptibility Contrast MRI from Regions around Arteries Using Independent Component Analysis

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Dynamic susceptibility contrast MRI

Introduction Quantitative dynamic susceptibility contrast perfusion MRI (DSC-MRI) is based on the monitoring of the first passage of a bolus of contrast agent through the brain tissue and a brain-feeding artery. The contrast agent is injected rapidly by means of an MRinjector in the antecubital vein in the patients arm and a saline flush is used to push the contrast agent into the direction of ...

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ژورنال

عنوان ژورنال: Magnetic Resonance in Medicine

سال: 2010

ISSN: 0740-3194,1522-2594

DOI: 10.1002/mrm.22420